MP4 (MPEG-4 Part 14) is a video container format based on QuickTime MOV. But unlike MOV, it adds support for other MPEG features. MP4 supports video (MPEG-4 Part 2 and MPEG-4 Part 10/H.264), audio (MP3, AAC, SLS, TTSI, and ALAC), and subtitles (MPEG-4 timed text). It’s this codec combination that gives MP4 its flexibility.
Windows Media Player VLC Media Player, Apple QuickTime Player 5KPLayer
M4R is a filename extension for AAC format, which is developed by Apple Inc. It is typically used to save custom iPhone ringtones from Apple iTunes. M4R can only be created from iTunes purchased songs and is usually DRM protected. It can open on iTunes, VLC Media Player, Apple QuickTime Player, and more.