MP4 (MPEG-4 Part 14) is a video container format based on QuickTime MOV. But unlike MOV, it adds support for other MPEG features. MP4 supports video (MPEG-4 Part 2 and MPEG-4 Part 10/H.264), audio (MP3, AAC, SLS, TTSI, and ALAC), and subtitles (MPEG-4 timed text). It’s this codec combination that gives MP4 its flexibility.
Windows Media Player VLC Media Player, Apple QuickTime Player 5KPLayer
F4V is a filename extension for Flash Video (FLV) container format. It supports H.264 (MPEG-4 AVC) video codec compression standard, which is known to offer significant compression. FLV videos come in multiple formats apart from F4V, including F4P, F4A, and F4B. Also, it opens on Adobe Flash Player 6 or later and Windows Media Player.
Windows Media Player Adobe Flash Player 6 or later Media Monkey