M4B is an audio filename extension for AAC format, which is developed by Apple Inc. It is mainly used on podcast and audiobook files. Typically, M4B files contain audio and other metadata like images, hyperlinks, and chapter markers. M4B files are DRM copy-protected and can be opened on Apple iTunes and QuickTime Player.
MP3 is a standard audio format developed by Moving Picture Experts Group and uses MPEG-1 and MPEG-2 standardizations. MP3 uses lossy data compression, meaning that it loses quality over time. This sound format comes with a .mp3 filename extension and is today the most common audio format on websites and multimedia players.
Windows Media Player iTunes, Mplayer VLC Media Player