M4A is a filename extension for AAC container format and is developed by Apple Inc. M4A music is bought on the iTunes Store and does not come with DRM protection. In terms of quality, M4A is better than MP3 because it is lossless but still compressed. This means that it occupies less storage space and doesn’t lose quality over time.
iTunes Apple QuickTime Player VLC Windows Media Player
MKV is a container format for holding multiple audio, video, picture, and text data such as subtitle tracks. It is similar to other common containers like MP4 and AVI, although MKV is open in the specification. For video contents, MKV uses a .mkv filename extension, .mka for audios, and .mks for subtitles.
MPC-HC, KMPlayer VLC Media Player MKV File Player MPV