M2TS (MPEG-2 Transport Stream) is a Blu-ray BDAV container format that uses MPEG-2 transport stream and comes with a .m2ts filename extension. It can manipulate audio, video, and other metadata such as disc menu and subtitles. At a bare minimum, any Blu-ray player should play M2TS files easily.
MKV is a container format for holding multiple audio, video, picture, and text data such as subtitle tracks. It is similar to other common containers like MP4 and AVI, although MKV is open in the specification. For video contents, MKV uses a .mkv filename extension, .mka for audios, and .mks for subtitles.
MPC-HC, KMPlayer VLC Media Player MKV File Player MPV