M2TS (MPEG-2 Transport Stream) is a Blu-ray BDAV container format that uses MPEG-2 transport stream and comes with a .m2ts filename extension. It can manipulate audio, video, and other metadata such as disc menu and subtitles. At a bare minimum, any Blu-ray player should play M2TS files easily.
M4V is a digital video container format developed by Apple Inc. It is pretty similar to the popular MP4 in terms of structure, but M4V files can sometimes be DRM protected. Today, M4V is the primary video format for iTunes Store videos and can multiplex together multiple audio and video data.
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