H.264 is a video compression standard used for HD videos. In fact, it’s the most widely-used video codec today. As such, this codec can be incorporated into several container formats like MP4, 3GP, MOV, FLV, and others. Most of the time, it’s encoded with the Advanced Audio Coding (AAC) codec.
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M4R is a filename extension for AAC format, which is developed by Apple Inc. It is typically used to save custom iPhone ringtones from Apple iTunes. M4R can only be created from iTunes purchased songs and is usually DRM protected. It can open on iTunes, VLC Media Player, Apple QuickTime Player, and more.