MPEG, sometimes called MPG, is a video file format popular for distributing content over the internet. It is the sister format to MP4 and MP3 because they share the same developer – Moving Picture Expert Group. MPG format uses either MPEG-2 or MPEG-1 compression, depending on the circumstance. Opening it is usually easy on any OS platform.
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M4B is an audio filename extension for AAC format, which is developed by Apple Inc. It is mainly used on podcast and audiobook files. Typically, M4B files contain audio and other metadata like images, hyperlinks, and chapter markers. M4B files are DRM copy-protected and can be opened on Apple iTunes and QuickTime Player.