MKV is a container format for holding multiple audio, video, picture, and text data such as subtitle tracks. It is similar to other common containers like MP4 and AVI, although MKV is open in the specification. For video contents, MKV uses a .mkv filename extension, .mka for audios, and .mks for subtitles.
MPC-HC, KMPlayer VLC Media Player MKV File Player MPV
FLV (Flash Video) is a video container format developed by Adobe Systems and comes with a .flv filename format. FLV is primarily used to stream audio, video, and text data such as subtitles. It supports MPEG-4 Part 10 (H.264) video codec and AAC sound.
RealPlayer, Apple QuicTime Player
VLC Media Player